Sharma M, Khaitan T, Raman S, Jain R, Kabiraj A.
Indian J Otolaryngol Head Neck Surg. 2019 Nov;71(Suppl 3):1957-1961. doi: 10.1007/s12070-018-1383-7. Epub 2018 May 2.
Allergic rhinitis is the most increasing allergic respiratory disorder. It affects 10-20% of the population and is clinically identified by symptoms such as nasal discharge, itching, sneezing and nasal congestion. The objectives of this study were to determine if serum IgE and eosinophil levels have a correlation with allergic rhinitis. A total of 155 participants (113 patients and 42 healthy controls, 81 women) of different ages (1 month – 75 years old) were included in this retrospective study. Blood samples were collected from all participants and analysed to determine serum IgE and eosinophil levels. A Pearson’s correlation was performed to establish a relationship between serum log IgE and eosinophil levels. The statistical analysis of the samples demonstrated that the mean values of serum found that these were higher in participants with allergic rhinitis than in healthy controls. Also, in participants with allergic rhinits, a predominance in men was seen in mean serum log IgE levels, whereas women predominance was seen in mean eosinophil counts. A small positive correlation was established between serum log IgE and eosinophil levels. This study showed that elevated serum IgE and eosinophil levels were observed in patients with allergic rhinitis with predominance in men and younger age group.
Serum IgE and eosinophils can serve as a simple, non-invasive and reliable tool for allergic rhinitis diagnosis.