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Allergen Immunotherapy archivos - Bilastina

Alergenos farmacoterapia e inmunologia

Responders and nonresponders to pharmacotherapy and allergen immunotherapy

By | Selected articles

Jakalski M, Bozek A, Canonica GW.

A retrospective analysis of 1624 patients with allergic rhinitis who underwent allergen immunotherapy and 1519 matched patients who underwent only symptomatic therapy was performed.

Allergen immunotherapy is a useful treatment for allergic rhinitis; however, some patients do not achieve the expected results and its responsiveness is difficult to assess. The objective of this study was to assess potential reasons for this to happen.

Investigators registered symptoms, medication scores and quality of life related to allergic diseases before and after treatment. A cluster analysis was performed to discover any association between responsiveness to therapy and the parameters registered.

According to the Mailing criteria, which assesses responsiveness to therapy, 77,8% of patients from the allergen immunotherapy group improved 30% or more; and 62,5% of patients met the threshold of 60% or more improvement. Patients with a short history of allergic rhinitis and concomitant allergy to grass pollen or house dust mites were more frequently worse responders to allergen immunotherapy.

In conclusion, the investigators suggest that short term allergic rhinitis and monovalent allergies to grass pollen or mites could correspond to a better response to allergen treatment.

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Rinitis alérgenos y asma en Bélgica

Stepwise approach towards adoption of allergen immunotherapy for allergic rhinitis and asthma patients in daily practice in Belgium: a BelSACI-Abeforcal-EUFOREA statement

By | Selected articles

Hellings PW, Pugin B, Mariën G, Bachert C, Breynaert C, et al.

Physicians dealing with Allergic rhinitis (AR) patients should inform patients on tolerance-inducing effects of Allergen immunotherapy (AIT) and are in the need of a harmonized and practical guide that supports them in selecting eligible patients for AIT, in choosing evidence-based AIT products and in following treatment protocols with proven efficacy. Therefore, a stepwise and holistic approach is needed for better adoption of AIT in the real-life setting in Belgium.

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