Chronic urticaria is an itchy skin disease, which is treated with antihistamines; however, a large group of patients are unresponsive to antihistamines alone and other treatments. This study presents an overview of studies investigating plasma D-dimer level as a biomarker for disease activity and treatment response in patients with chronic urticaria.
Chronic urticaria (CU) is a common disease, characterized by the development of wheals, angioedema, or both. CU reduces quality of life and can also cause emotional distress. The data of this study demonstrate that depression and anxiety symptoms are more common in patients with chronic urticaria than in the control group. Therefore, we should pay attention to the potential of mental comorbidities while managing patients with CU.